Experimental Type 2 diabetes and lipotoxicity-associated neuroinflammation involve mitochondrial DNA-mediated cGAS/STING axis: implication of Type-1 interferon response in cognitive impairment
Preeti Kumari, Anika Sood, Valencia Fernandes, Islauddin Khan, Dharmendra Kumar Khatri, Shashi Bala Singh
Topics & Concepts
LipotoxicityIRF3EndocrinologyInternal medicineNeuroinflammationProinflammatory cytokineSTAT1BiologyInterferonImmunologyMedicineDiabetes mellitusInflammationInnate immune systemInsulin resistanceReceptorinterferon and immune responsesInflammasome and immune disordersImmune cells in cancer