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Pyridazine derivative as potent antihyperglycemic agent: Synthesis, crystal structure, α-amylase and α-glucosidase inhibition and computational studies

Hamza Assila, Silvia Antonia Brandán, Salma Mortada, Younes Zaoui, Abdullah Yahya Abdullah Alzahrani, Suhana Arshad, Youssef Ramli, My El Abbés Faouzi, Khalid Karrouchi, M’hammed Ansar

2024Journal of Molecular Structure14 citationsDOI

Topics & Concepts

ChemistryPyridazineDensity functional theoryPDZ domainNatural bond orbitalCrystallographyDocking (animal)AcarboseStereochemistryProton NMRComputational chemistryOrganic chemistryEnzymeBiochemistryNursingMedicineComputational Drug Discovery MethodsNatural Antidiabetic Agents StudiesEnzyme function and inhibition
Pyridazine derivative as potent antihyperglycemic agent: Synthesis, crystal structure, α-amylase and α-glucosidase inhibition and computational studies | Litcius