CAR-T cell therapy in hepatocellular carcinoma: from mechanistic insights to clinical translation
Reza Elahi, Yassine Alami Idrissi, Anwaar Saeed
Topics & Concepts
Chimeric antigen receptorMedicineReprogrammingImmunotherapyHepatocellular carcinomaCancer researchStromal cellCell therapyCancerTranslational researchImmune systemTumor microenvironmentTranslation (biology)Targeted therapyAntigenComputational biologyCancer therapyBioinformaticsTyrosine kinaseImmune checkpointCytokineClinical trialCancer immunotherapyCellReceptor tyrosine kinaseImmunologyCombination therapyCancer cellGenetic enhancementCytokine release syndromeCAR-T cell therapy researchImmunotherapy and Immune ResponsesVirus-based gene therapy research