Changes in Liver Enzymes and Metabolic Profile in Adolescents with Fatty Liver following Exercise Interventions
Hamdollah Iraji, Vazgen Minasian, Roya Kelishadi
Abstract
Purpose: Nonalcoholic fatty liver disease (NAFLD) is the most frequent cause of chronic liver diseases in both adults and children with obesity. The aim of this study was to compare the changes in liver enzymes and metabolic profile in adolescents with fatty liver following selected school-based exercise (SBE) and high-intensity interval training (HIIT) interventions. Methods: In a semi-experimental study, 34 obese male adolescents with clinically defined NAFLD were divided into the HIIT (n=11, age=12.811.02 years, body mass index [BMI]=26.68 2.32 kg/m 2 ), selected SBE (n=11, age=13.390.95 years, BMI=26.471.74 kg/m 2 ), and control (n=12, age=13.141.49 years, BMI=26.452.21 kg/m 2 ) groups. The ultrasonography NAFLD grade, peak oxygen uptake (VO 2peak ), lipid profile, insulin resistance, and alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels of the participants were measured before and after the exercise interventions.