Discovery of novel akt1 inhibitor induces autophagy associated death in hepatocellular carcinoma cells
Meng Yu, Minghui Zeng, Zhaoping Pan, Fengbo Wu, Li Guo, Gu He
Topics & Concepts
AKT1AutophagyChemistryPI3K/AKT/mTOR pathwayProtein kinase BProgrammed cell deathCell growthIC50Hepatocellular carcinomaCell cultureCancer researchPharmacologyIn vitroSignal transductionApoptosisBiochemistryBiologyGeneticsPI3K/AKT/mTOR signaling in cancerAutophagy in Disease and TherapyBiochemical and Molecular Research