Oropouche virus detection in saliva and urine
Valdinete Alves do Nascimento, João Hugo Abdalla Santos, Dana Cristina da Silva Monteiro, Karina Pessoa, Antonio José Leão Cardoso, Victor Costa de Souza, Lígia Fernandes Abdalla, Felipe Gomes Naveca
Abstract
Oropouche virus (OROV) is an arthropod-borne virus of the Peribunyaviridae family, transmitted to humans primarily by Culicoides paraensis. It is one of the main arboviruses infecting humans in Brazil, primarily in the Amazon Region. Here, we report the detection of OROV in the saliva and urine of a patient whose samples were collected five days after the onset of symptoms. Nucleotide sequencing and phylogenetic analysis further confirmed the results. To our knowledge, this is the first study reporting the detection of OROV in the saliva and urine of an infected patient. In addition, the results of our study expand the current knowledge pertaining to the natural history of Oropouche fever.