A mitochondrion-targeting Mn(<scp>ii</scp>)-terpyridine complex for two-photon photodynamic therapy
Xinda Yang, Duoteng Zhang, Jie Li, Wenhui Ji, Naidi Yang, Shunxin Gu, Qiong Wu, Qin Jiang, Pengfei Shi, Lin Li
Abstract
A mitochondrion-targeting Mn<sup>II</sup>-terpyridine complex (MTP) has been developed for providing a good spatial condition to generate <sup>1</sup>O<sub>2</sub>, which further promoted the two-photon photodynamic therapy (PDT) effect.
Topics & Concepts
TerpyridinePhotodynamic therapyMitochondrionChemistryTwo-photon excitation microscopyPhotosensitizerBiophysicsNuclear chemistryPhotochemistryPhysicsBiochemistryFluorescenceOpticsMetalBiologyOrganic chemistryPorphyrin and Phthalocyanine ChemistryNanoplatforms for cancer theranosticsPhotodynamic Therapy Research Studies