Bioconjugates of versatile β-diketonate–lanthanide complexes as probes for time-gated luminescence and magnetic resonance imaging of cancer cells <i>in vitro</i> and <i>in vivo</i>
Bo Song, Xinyi Wen, Xinyue Zhang, Qi Liu, Hua Ma, Mingqian Tan, Jingli Yuan
Abstract
as probes, the cultured cancerous cells and the tumors in tumor-bearing mice have been clearly visualized by background-free TGL and in vivo MR imaging. The research outcomes suggested the potential of β-diketonate-lanthanide complexes for use in constructing bimodal TGL/MR imaging bioprobes.
Topics & Concepts
LanthanideLuminescenceIn vivoIn vitroMagnetic resonance imagingMaterials scienceNuclear magnetic resonanceNanotechnologyChemistryOptoelectronicsBiochemistryOrganic chemistryMedicineBiologyIonPhysicsRadiologyBiotechnologyLanthanide and Transition Metal ComplexesMedical Imaging Techniques and ApplicationsAdvanced MRI Techniques and Applications