Litcius/Paper detail

Hybrid molecules of thiadiazole-based benzothioate and benzenesulfonothioate: synthesis, structural analysis, and evaluation as potential inhibitors of thymidine phosphorylase and β-glucuronidase through in vitro and in silico approaches

Yousaf Khan, Shoaib Khan, Wajid Rehman, Rafaqat Hussain, Aneela Maalik, Farhan Ali, Muhammad Usman Ghani Khan, Abdul Sattar, Mohammed A. Assiri

2023Journal of Molecular Structure22 citationsDOI

Topics & Concepts

ChemistryThymidine phosphorylaseThymidineIC50EnzymeIn vitroStereochemistryGlycogen phosphorylaseBiochemistryBiochemical and Molecular ResearchSynthesis and biological activityHIV/AIDS drug development and treatment