Litcius/Paper detail

A plausible metal-free ancestral analogue of the Krebs cycle composed entirely of α-ketoacids

R. Trent Stubbs, Mahipal Yadav, Ramanarayanan Krishnamurthy, Greg Springsteen

2020Nature Chemistry119 citationsDOIOpen Access PDF

Topics & Concepts

Glyoxylate cycleChemistryTransaminationCitric acid cycleMetabolic pathwayEnzymeCombinatorial chemistryBiochemistryOrigins and Evolution of LifeAmino Acid Enzymes and MetabolismEnzyme Structure and Function