R-type voltage-gated Ca<sup>2+</sup> channels mediate A-type K<sup>+</sup> current regulation of synaptic input in hippocampal dendrites.
Jonathan G. Murphy, Jakob J. Gutzmann, Lin Lin, Jiahua Hu, Ronald S. Petralia, Yaxian Wang, Dax A. Hoffman
Abstract
influx. These results propose that Cav2.3 and Kv4.2 are integral constituents of an ion channel complex that affects synaptic function in the hippocampus.
Topics & Concepts
AMPA receptorSynaptic plasticityNeuroscienceHippocampal formationProtein subunitDendritic spineChemistryGlutamate receptorLong-term potentiationHippocampusCell biologyVoltage-dependent calcium channelNMDA receptorIon channelDendrite (mathematics)R-type calcium channelVoltage-gated ion channelSynapseBiophysicsBiologyReceptorT-type calcium channelCalciumBiochemistryOrganic chemistryMathematicsGeneGeometryIon channel regulation and functionNeuroscience and Neuropharmacology ResearchNeuroscience and Neural Engineering