Design of next-generation covalent inhibitors: Targeting residues beyond cysteine
Lyn H. Jones
Topics & Concepts
CysteineCovalent bondChemistryElectrophileSerineChemical biologyHistidineAmino acidLysineCombinatorial chemistrySmall moleculeThreonineTyrosineDrug discoveryBiochemistryEnzymeOrganic chemistryCatalysisClick Chemistry and ApplicationsChemical Synthesis and AnalysisPeptidase Inhibition and Analysis