Exosomal lncRNA GAS5 promotes M1 macrophage polarization in allergic rhinitis via restraining mTORC1/ULK1/ATG13-mediated autophagy and subsequently activating NF-кB signaling
Xiaoyuan Zhu, Yudong Sun, Qianjiang Yu, Xueping Wang, Ying Wang, Yulin Zhao
Topics & Concepts
Macrophage polarizationmTORC1Sequestosome 1AutophagyGene knockdownDownregulation and upregulationCancer researchChemistryMolecular biologyMacrophageSignal transductionBiologyCell biologyIn vitroPI3K/AKT/mTOR pathwayBiochemistryApoptosisGeneCancer-related molecular mechanisms researchExtracellular vesicles in diseaseViral Infections and Vectors