Tumor Lysis Syndrome in a Patient With Metastatic Endometrial Cancer Treated With Lattice Stereotactic Body Radiation Therapy
Joshua P. Schiff, Matthew B. Spraker, Sai Duriseti, Sana Shaikh, Haris Murad, David G. Mutch, Clifford G. Robinson, James Kavanaugh, Alexander J. Lin
Abstract
Spatially fractionated radiation therapy is hypothesized to allow for safe, hypofractionated, dose- escalated radiation therapy for large tumors.1-3 Spatially fractionated radiation therapy can be delivered in a grid-like pattern (ie, GRID) using 3-dimensional conformal planning techniques. It can also be delivered using intensity modulated radiation therapy (ie, lattice radiation therapy). Lattice delivers a low dose to a gross tumor volume (GTV) with high dose spherical vertices spaced within the tumor, which has previously been described in small case series of patients with gynecologic and other malignancies.