Substrate-controlled C–H or C–C alkynylation of cyclopropanes: generation of aryl radical cations by direct light activation of hypervalent iodine reagents
Tin V. T. Nguyen, Matthew D. Wodrich, Jérôme Waser
Abstract
C–C or C–H alkynylation of aryl cyclopropanes was realized by direct activation of EBX reagents with visible light. With ortho methyl groups on the benzene, C–H functionalization became favoured.
Topics & Concepts
Hypervalent moleculeArylIodineAlkynylationReagentChemistrySubstrate (aquarium)PhotochemistryCombinatorial chemistryMedicinal chemistryCatalysisOrganic chemistryAlkylOceanographyGeologyOxidative Organic Chemistry ReactionsCatalytic C–H Functionalization MethodsRadical Photochemical Reactions