Feeding induces cholesterol biosynthesis via the mTORC1–USP20–HMGCR axis
Xiao-Yi Lu, Xiongjie Shi, Ao Hu, Ju-Qiong Wang, Yi Ding, Wei Jiang, Ming Sun, Xiaolu Zhao, Jie Luo, Wei Qi, Bao‐Liang Song
Topics & Concepts
BiosynthesismTORC1CholesterolNPC1Cell biologyChemistryBiologyEndocrinologyBiochemistryGeneSignal transductionPI3K/AKT/mTOR pathwayIntracellularEndosomeCholesterol and Lipid MetabolismCancer, Lipids, and MetabolismLipid metabolism and biosynthesis