New series of isoxazole derivatives targeting EGFR-TK: Synthesis, molecular modeling and antitumor evaluation
Eman T. Warda, Ihsan A. Shehata, Mahmoud B. El‐Ashmawy, Nadia S. El‐Gohary
Topics & Concepts
ChemistryCancer cellApoptosisCytotoxicityCell cycle checkpointIC50IsoxazoleCell cycleDocking (animal)In vitroCaspaseProgrammed cell deathCancer researchCancerPharmacologyBiochemistryStereochemistryBiologyMedicineGeneticsNursingCancer therapeutics and mechanismsSynthesis and biological activityLung Cancer Treatments and Mutations