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Synthesis of novel potent cytotoxicy podophyllotoxin-naphthoquinone compounds via microwave-assited multicomponent domino reactions

Quynh Giang Nguyen Thi, Giang Le-Nhat-Thuy, Tuyet Anh Dang Thi, Tuyet Anh Dang Thi, Phượng Hoàng Thị, Anh Nguyen Tuan, Thu Ha Nguyen Thi, Thu Ha Nguyen Thi, Thanh Tra Nguyen, Ha Thanh Nguyen, Ha Hoang Mai, Tuyen Van Nguyen

2021Bioorganic & Medicinal Chemistry Letters26 citationsDOI

Topics & Concepts

PodophyllotoxinChemistryCytotoxicityNaphthoquinoneAmmonium acetateCell cultureCombinatorial chemistryDominoHEK 293 cellsChemical synthesisStereochemistryIn vitroBiochemistryOrganic chemistryGeneticsHigh-performance liquid chromatographyGeneBiologyCatalysisPlant-derived Lignans Synthesis and BioactivityBioactive Compounds and Antitumor AgentsMulticomponent Synthesis of Heterocycles
Synthesis of novel potent cytotoxicy podophyllotoxin-naphthoquinone compounds via microwave-assited multicomponent domino reactions | Litcius