A Nanoparticle-Based Anticaries Vaccine Enhances the Persistent Immune Response To Inhibit Streptococcus mutans and Prevent Caries
You-Bo Yu, Ying Liu, Hangeri Liang, Xianxin Dong, Xiao-Yan Yang, Sha Li, Zhong Guo
Abstract
Streptococcus mutans is the main etiologic bacterium of dental caries, whose protein antigen c (PAc) has been administered as an anticaries vaccine. However, the immunogenicity of PAc is relatively weak.
Topics & Concepts
Streptococcus mutansImmune systemMicrobiologyChemistryBiologyImmunologyBacteriaGeneticsOral microbiology and periodontitis researchStreptococcal Infections and TreatmentsNeonatal and Maternal Infections