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Dissecting Cellular Function and Distribution of β-Glucosidases in Trichoderma reesei

Aiping Pang, Haiyan Wang, Yongsheng Luo, Zihuayuan Yang, Zhiyu Liu, Zhao Wang, Bing‐Zhi Li, Song Yang, Zhihua Zhou, Xiaolin Lü, Fu‐Gen Wu, Zuhong Lu, Fengming Lin

2021mBio78 citationsDOIOpen Access PDF

Abstract

Specially, CEL3C was located in the nucleus. CEL3J was secreted through the nonclassical protein secretion pathway bypassing endoplasmic reticulum (ER) and Golgi. CEL1A was secreted via a vacuole-mediated conventional secretion route without a signal peptide. These findings advance our understanding of β-glucosidase properties and secretory pathways in filamentous fungi, holding key clues for future study.

Topics & Concepts

Trichoderma reeseiGlucosidasesFunction (biology)Computational biologyTrichodermaBiologyChemistryBiotechnologyBiochemistryCell biologyEnzymeCellulaseBiofuel production and bioconversionEnzyme Production and CharacterizationMicrobial Metabolic Engineering and Bioproduction