Targeting ubiquitin conjugating enzyme UbcH5b by a triterpenoid PC3-15 from Schisandra plants sensitizes triple-negative breast cancer cells to lapatinib
Maobo Huang, Yuan‐Fei Zhou, Dongzhu Duan, Chuanyu Yang, Zhongmei Zhou, Fubing Li, Yanjie Kong, Yi-Ching Hsieh, Ruihan Zhang, Wenping Ding, Wei‐Lie Xiao, Pema‐Tenzin Puno, Ceshi Chen
Topics & Concepts
LapatinibUbiquitinUbiquitin-conjugating enzymeCancer researchEnzymeAutophagyChemistryBiochemistryBiologyCancerBreast cancerUbiquitin ligaseApoptosisGeneticsTrastuzumabGeneUbiquitin and proteasome pathwaysAutophagy in Disease and TherapyHistone Deacetylase Inhibitors Research