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Enhancing the selectivity of prolinamide organocatalysts using the mechanical bond in [2]rotaxanes

María Calles García, Julio Puigcerver, Diego A. Alonso, Mateo Alajarı́n, Alberto Martínez‐Cuezva, José Berná

2020Chemical Science36 citationsDOIOpen Access PDF

Abstract

-hexylthymine as a cofactor to form supramolecular catalysts displaying a divergent catalytic behaviour. The presence or absence of the cofactor controls the chemoselectivity in competitive reactions.

Topics & Concepts

SelectivityChemistryOrganic chemistryCatalysisAsymmetric Synthesis and CatalysisCrystallography and molecular interactionsSupramolecular Chemistry and Complexes
Enhancing the selectivity of prolinamide organocatalysts using the mechanical bond in [2]rotaxanes | Litcius