Bioreactivity of a novel poly(epsilon-caprolactone) nanocapsule containing atrazine with human lung alveolar epithelial cells
Amber Moore, Lareb S. N. Dean, Aiken Yam, Renata de Lima, Leonardo Fernandes Fraceto, Teresa D. Tetley
Abstract
Nanoencapsulation of pesticide atrazine improves efficacy. However, this study discovered adverse bioreactivity in alveolar type 1 epithelial cells (a major recipient of inhaled nano-sized particles), following exposure to nanoencapsulated atrazine.
Topics & Concepts
AtrazineHuman lungCaprolactoneIntratracheal instillationNanocapsulesLungMaterials scienceChemistryPesticideNanotechnologyMedicineNanoparticleBiologyComposite materialInternal medicinePolymerizationEcologyBronchoalveolar lavagePolymerPesticide and Herbicide Environmental StudiesPesticide Exposure and ToxicityEnvironmental Toxicology and Ecotoxicology