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Biased allosteric activation of ketone body receptor HCAR2 suppresses inflammation

Chang Zhao, Heli Wang, Ying Liu, Lin Cheng, Bo Wang, Xiaowen Tian, Hong Fu, Chao Wu, Ziyan Li, Chenglong Shen, Jingjing Yu, Shengyong Yang, Hongbo Hu, Ping Fu, Liang Ma, Chuanxin Wang, Wei Yan, Zhenhua Shao

2023Molecular Cell44 citationsDOIOpen Access PDF

Topics & Concepts

Allosteric regulationNiacinPharmacologyBiologyReceptorAllosteric modulatorEffectorInflammationBiochemistryImmunologyPeroxisome Proliferator-Activated ReceptorsTryptophan and brain disordersReceptor Mechanisms and Signaling
Biased allosteric activation of ketone body receptor HCAR2 suppresses inflammation | Litcius