Oligomeric phenylpropanoids having new skeletons and hypoglycemic activity from <i>Magnolia officinalis</i> var. <i>biloba</i>
Kailing Xu, Chuan Li, Chuang‐Jun Li, Jie Ma, Yingda Zang, Fei Ye, Dongming Zhang
Abstract
Three oligomeric phenylpropanoids [(+)/(–)-1 and 2] with new skeletons and a meroterpenoid (3) from Magnolia officinalis var. biloba were identified. Pharmacological studies showed(+)-1 and (–)-1 are PTP1B and α-glucosidase dual inhibitors.
Topics & Concepts
Magnolia officinalisChemistryTraditional medicineOfficinalisMagnoliaceaeBotanyBiologyTraditional Chinese medicineAlternative medicinePathologyMedicineMagnolia and Illicium researchPhytochemistry and Bioactive CompoundsPlant-derived Lignans Synthesis and Bioactivity