Immunodepletion of MDSC by AMV564, a novel bivalent, bispecific CD33/CD3 T cell engager, ex vivo in MDS and melanoma
Pingyan Cheng, Xianghong Chen, Robert Dalton, Alexandra Calescibetta, Tina So, Danielle L. Gilvary, Grace Ward, Victoria Smith, Sterling Eckard, Judith A. Fox, Jeanmarie Guenot, Joseph Markowitz, John L. Cleveland, Kenneth L. Wright, Alan F. List, Sheng Wei, Erika A. Eksioglu
Topics & Concepts
Bivalent (engine)Ex vivoMelanomaCancer researchIn vivoCD3ChemistryMolecular biologyBiologyImmunologyImmune systemGeneticsCD8Organic chemistryMetalCAR-T cell therapy researchImmunotherapy and Immune ResponsesT-cell and B-cell Immunology