Litcius/Paper detail

PARP trapping is governed by the PARP inhibitor dissociation rate constant

Angelica A. Gopal, Bianca Fernandez, Justin Delano, Ralph Weissleder, J. Matthew Dubach

2024Cell chemical biology26 citationsDOIOpen Access PDF

Topics & Concepts

Poly ADP ribose polymerasePARP1PolymeraseDNAChemistryDNA damagePotencyMolecular biologyBiologyBiophysicsCancer researchIn vitroBiochemistryPARP inhibition in cancer therapyDNA Repair MechanismsIntegrated Circuits and Semiconductor Failure Analysis