CRISPR base editing of cis-regulatory elements enables the perturbation of neurodegeneration-linked genes
Colin K.W. Lim, Tristan X. McCallister, Christian Saporito-Magriñá, Garrett D. McPheron, Ramya Krishnan, M. Alejandra Zeballos C., Jackson E. Powell, Lindsay V. Clark, Pablo Pérez‐Piñera, Thomas Gaj
Topics & Concepts
BiologyCRISPRGeneGene expressionGenome editingRegulation of gene expressionComputational biologyGeneticsRNA editingTranscription (linguistics)Cas9LinguisticsPhilosophyCRISPR and Genetic EngineeringRNA regulation and diseaseViral Infections and Immunology Research