Panaxadiol as a major metabolite of AD-1 can significantly inhibit the proliferation and migration of breast cancer cells: In vitro and in vivo study
Lei Xu, Xiaoshu Zhang, Shengnan Xiao, Xiaofei Li, Hua Jiang, Ziyi Wang, Baoshan Sun, Yuqing Zhao
Topics & Concepts
In vivoIn vitroChemistryMetaboliteCyclin D1Cyclin-dependent kinase 6TranscriptomeCancer researchMMP9Breast cancerMAPK/ERK pathwayCancerCell cycleSignal transductionDownregulation and upregulationApoptosisBiologyBiochemistryGene expressionGeneGeneticsBiotechnologyGinseng Biological Effects and ApplicationsBiological Activity of Diterpenoids and BiflavonoidsHops Chemistry and Applications