Safety and immunogenicity of heterologous boost immunisation with an orally administered aerosolised Ad5-nCoV after two-dose priming with an inactivated SARS-CoV-2 vaccine in Chinese adults: a randomised, open-label, single-centre trial
Jingxin Li, Shipo Wu, Xiling Guo, Rong Tang, Baoying Huang, Xiaoqin Chen, Yin Chen, Li-Hua Hou, Jing-Xian Liu, Jin Zhong, Hongxing Pan, Fengjuan Shi, Xiaoyu Xu, Zhuo-Pei Li, Xiao-Yin Zhang, Lunbiao Cui, Wenjie Tan, Wei Chen, Fengcai Zhu, Jingxin Li, Shipo Wu, Xiling Guo, Rong Tang, Baoying Huang, Xiaoqin Chen, Yin Chen, Li-Hua Hou, Jing-Xian Liu, Jin Zhong, Hongxing Pan, Fengjuan Shi, Xiaoyu Xu, Zhuo-Pei Li, Xiao-Yin Zhang, Lunbiao Cui, Wenjie Tan, Wei Chen, Fengcai Zhu, Hai-Tao Huang, Jin-Bo Gou, Weixue Si, Xue Wang, Xiaolong Zhao, Tao Zhu
Topics & Concepts
MedicineImmunogenicitySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)2019-20 coronavirus outbreakCoronavirus disease 2019 (COVID-19)VirologyHeterologousPriming (agriculture)PharmacologyImmunologyImmune systemInternal medicineBiologyOutbreakGeneBotanyInfectious disease (medical specialty)GerminationDiseaseChemistryBiochemistrySARS-CoV-2 and COVID-19 ResearchIntramuscular injections and effectsAnimal Virus Infections Studies