RIOK1 mediates p53 degradation and radioresistance in colorectal cancer through phosphorylation of G3BP2
Yaqi Chen, Sha Zhou, Kairui Wan, Long Yu, Chongchong Zhao, Haiteng Deng, Qingjian Ou, Jiayi Qin, Junbo Hu, Zhenlin Hou
Topics & Concepts
RadioresistanceColorectal cancerBiologyCancer researchMdm2CancerPhosphorylationKinaseIn vivoRadiation therapyInternal medicineCell cultureMedicineCell biologyGeneticsCancer-related Molecular PathwaysUbiquitin and proteasome pathwaysCell death mechanisms and regulation