Synthesis of hydrazone-based polyhydroquinoline derivatives – antibacterial activities, α-glucosidase inhibitory capability, and DFT study
Muhammad Shoaib Ismail, Rashid Ahmad, Sobia Ahsan Halim, Adnan Ali Khan, Naeem Ullah, Abdul Latif, Manzoor Ahmad, Ajmal Khan, Fethi Ahmet Özdemir, Asaad Khalid, Ahmed Al‐Harrasi, Mumtaz Ali
Abstract
= 6.51 ± 0.37 μM). Furthermore, molecular docking and DFT analysis of these compounds showed good agreement with experimental work and the nonlinear optical properties calculated here indicate that these compounds are good candidates for nonlinear optics.
Topics & Concepts
HydrazoneChemistryInhibitory postsynaptic potentialCombinatorial chemistryAntibacterial activityStereochemistryComputational chemistryPharmacologyBacteriaMedicineBiologyInternal medicineGeneticsSynthesis and biological activityMulticomponent Synthesis of HeterocyclesSynthesis and Characterization of Heterocyclic Compounds