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Non-invasive transabdominal measurement of placental oxygenation: a step toward continuous monitoring

Thien Nguyen, Kosar Khaksari, Siddharth Khare, Soongho Park, Afrouz Anderson, Janine Bieda, Eunjung Jung, Chaur‐Dong Hsu, Roberto Romero, Amir Gandjbakhche

2021Biomedical Optics Express17 citationsDOIOpen Access PDF

Abstract

This study aimed to assess transabdominal placental oxygenation levels non-invasively. A wearable device was designed and tested in 12 pregnant women with an anterior placenta, 5 of whom had maternal pregnancy complications. Preliminary results revealed that the placental oxygenation level is closely related to pregnancy complications and placental pathology. Women with maternal pregnancy complications were found to have a lower placental oxygenation level (69.4% ± 6.7%) than those with uncomplicated pregnancy (75.0% ± 5.8%). This device is a step in the development of a point-of-care method designed to continuously monitor placental oxygenation and to assess maternal and fetal health.

Topics & Concepts

MedicinePregnancyPlacentaOxygenationObstetricsFetusAnesthesiaBiologyGeneticsMaternal and fetal healthcarePregnancy and preeclampsia studiesMaternal and Perinatal Health Interventions