Downregulation of redox imbalance and iNOS/NF-ĸB/caspase-3 signalling with zinc supplementation prevents urotoxicity of cyclophosphamide-induced hemorrhagic cystitis in rats
Ademola C. Famurewa, Chuks Oswald Edeogu, Florence I Offor, E.E. Besong, G.G. Akunna, Ekenechukwu K. Maduagwuna
Topics & Concepts
Proinflammatory cytokineSuperoxide dismutaseChemistryNitric oxide synthaseMalondialdehydeGlutathioneHemorrhagic cystitisGlutathione peroxidasePharmacologyOxidative stressNitric oxideEndocrinologyTumor necrosis factor alphaInternal medicineInflammationMedicineCyclophosphamideBiochemistryChemotherapyEnzymeChemotherapy-induced organ toxicity mitigationPolyomavirus and related diseasesBladder and Urothelial Cancer Treatments