CXCL10 mediates CD8+ T cells to facilitate vessel normalization and improve the efficacy of cetuximab combined with PD-1 checkpoint inhibitors in colorectal cancer
Wei Yan, Lin Qiu, Meiling Yang, Anran Xu, Manqi Ma, Qinzi Yuan, Xiaochen Ma, Wenjuan Liang, Xuenong Li, Yanxia Lu
Topics & Concepts
CetuximabColorectal cancerCXCL10Cancer researchImmunotherapyMedicineCD8Cytotoxic T cellChemokineImmune systemImmunologyBiologyCancerInternal medicineIn vitroBiochemistryCancer Immunotherapy and BiomarkersImmune Cell Function and InteractionChemokine receptors and signaling