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Leveraging extrachromosomal DNA to fine-tune trials of targeted therapy for glioblastoma: opportunities and challenges

Imran Noorani, Paul S. Mischel, Charles Swanton

2022Nature Reviews Clinical Oncology65 citationsDOIOpen Access PDF

Topics & Concepts

GlioblastomaClinical trialMedicineSelection (genetic algorithm)Translation (biology)Computational biologyBioinformaticsBiologyCancer researchGeneticsComputer scienceGeneMessenger RNAArtificial intelligenceCancer Genomics and DiagnosticsGlioma Diagnosis and TreatmentSingle-cell and spatial transcriptomics
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