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A novel functional beverage for COVID-19 and other conditions: Hypothesis and preliminary data, increased blood flow, and wound healing

LeBaron TW, McCullough Ml, Ruppman Sr KH

2020Journal of Translational Science17 citationsDOIOpen Access PDF

Abstract

COVID-19 is caused by a viral infection, and can be a lethal disease to the immunocompromised.HydroShot is a popular functional health beverage that is infused with molecular hydrogen, and contains the nitric-oxide-producing amino acid citrulline.Numerous pre-clinical and clinical studies have demonstrated that the gaseous-signaling molecules, molecular hydrogen and nitric oxide, have anti-oxidant, anti-inflammatory, and immuno-modulating benefits.Although nitric oxide can directly kill pathogens, it is critical for immune function, can inhibit viral replication, and can also induce lethal cellular injury under stressed conditions.In contrast, molecular hydrogen has a very high safety profile and helps regulate nitric oxide production, metabolism, and attenuates its harmful effects.Both of these molecules are being used separately in clinical trials for COVID-19 patients.This article briefly reviews the scientific literature on these two molecules, and then presents preliminary data on HydroShot including increased blood flow and wound healing.Based on the pre-clinical, clinical, and this preliminary data, HydroShot is recommended for clinical testing/application in addition to its frequent consumer use.

Topics & Concepts

Nitric oxideClinical trialWound healingCitrullineImmune systemCoronavirus disease 2019 (COVID-19)PharmacologyMedicineNitric oxide synthaseImmunologyChemistryDiseaseArginineBiochemistryAmino acidPathologyInternal medicineInfectious disease (medical specialty)Hydrogen's biological and therapeutic effectsMedical and Biological Ozone ResearchAnesthesia and Neurotoxicity Research
A novel functional beverage for COVID-19 and other conditions: Hypothesis and preliminary data, increased blood flow, and wound healing | Litcius