Coming together at the hinges: Therapeutic prospects of IgG3
Thach H. Chu, Edward F. Patz, Margaret E. Ackerman
Abstract
ADCC - Antibody-Dependent Cell-mediated CytotoxicityADE - Antibody-dependent enhancementAID - Activation-Induced Cytidine DeaminaseCH - Constant HeavyCHF - Complement factor HCSR - Class Switch RecombinationEM - Electron MicroscopyFab - Fragment, antigen bindingFc - Fragment, crystallizableFcRn - Neonatal Fc ReceptorFcγR - Fc gamma ReceptorHIV - Human Immunodeficiency VirusIg - ImmunoglobulinIgH - Immunoglobulin Heavy chain geneNHP - Non-Human Primate.
Topics & Concepts
HingeComputer scienceComputational biologyBiologyEngineeringMechanical engineeringMonoclonal and Polyclonal Antibodies ResearchNeuroendocrine Tumor Research AdvancesIgG4-Related and Inflammatory Diseases