Gaseous metabolites as therapeutic targets in ulcerative colitis
Chu K Yao, Chen Sarbagili-Shabat
Abstract
S reduction. Conversely, very little is known regarding how diet alters microbial production of NO. Hence, the current evidence suggest that a whole diet approach is needed. Finally, biomarkers for assessing changes in microbial gaseous metabolites in response to dietary interventions are very much required. In conclusion, this review identifies a great need for high quality randomised-controlled trials to demonstrate the efficacy of a sulphide-reducing dietary therapy for patients with active UC.
Topics & Concepts
Ulcerative colitisMedicineHydrogen sulfideHydrogen sulphideNitric oxideIntensive care medicinePhysiologyDiseaseChemistryInternal medicineSulfurOrganic chemistryGut microbiota and healthDietary Effects on HealthGenomics, phytochemicals, and oxidative stress