Nonessential Ribosomal Proteins in Bacteria and Archaea Identified Using Clusters of Orthologous Genes
Michael Y. Galperin, Yuri I. Wolf, Sofya K. Garushyants, Roberto Vera Alvarez, Eugene V. Koonin
Abstract
In many prokaryote genomes, one or more ribosomal protein (RP) genes are missing. Analysis of 1,309 prokaryote genomes included in the Clusters of Orthologous Genes (COG) database shows that only about half of the RPs are universally conserved in bacteria and archaea.
Topics & Concepts
BiologyGenomeRibosomal proteinGeneticsProkaryoteGeneRibosomal RNARibosomeBacterial genome sizeArchaeaPseudogeneGenome projectComputational biologyRNARNA and protein synthesis mechanismsGenomics and Phylogenetic StudiesRNA modifications and cancer