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Gamma-mangostin isolated from garcinia mangostana suppresses colon carcinogenesis and stemness by downregulating the GSK3β/β-catenin/CDK6 cancer stem pathway

Alexander T.H. Wu, Yuan-Chieh Yeh, Yan‐Jiun Huang, Ntlotlang Mokgautsi, Bashir Lawal, Tse‐Hung Huang

2021Phytomedicine24 citationsDOI

Topics & Concepts

Garcinia mangostanaCyclin-dependent kinase 6Wnt signaling pathwayGSK-3Cancer stem cellCancer researchCateninColorectal cancerStem cellChemistryCancerBiologySignal transductionMedicineCyclin D1Cell cycleCell biologyTraditional medicineInternal medicineNatural Compound Pharmacology StudiesCancer Cells and MetastasisWnt/β-catenin signaling in development and cancer
Gamma-mangostin isolated from garcinia mangostana suppresses colon carcinogenesis and stemness by downregulating the GSK3β/β-catenin/CDK6 cancer stem pathway | Litcius