Design, synthesis, and biological evaluation of carbamate derivatives of N-salicyloyl tryptamine as multifunctional agents for the treatment of Alzheimer's disease
Dan Liu, Honghua Zhang, Yuying Wang, Wencheng Liu, Gaofeng Yin, Degui Wang, Junfang Li, Tao Shi, Zhen Wang
Topics & Concepts
AcetylcholinesteraseButyrylcholinesteraseChemistryTryptamineCarbamatePharmacologyNeuroinflammationAchéCholinesteraseBlood–brain barrierStereochemistryBiochemistryEnzymeCentral nervous systemInternal medicineDiseaseMedicineCholinesterase and Neurodegenerative DiseasesComputational Drug Discovery MethodsMedicinal Plants and Neuroprotection