SOCE as a regulator of neuronal activity
Raphaël Courjaret, Murali Prakriya, Khaled Machaca
Abstract
entry (SOCE) is a ubiquitous signalling module with established roles in the immune system, secretion and muscle development. Recent evidence supports a complex role for SOCE in the nervous system. In this review we present an update of the current knowledge on SOCE function in the brain with a focus on its role as a regulator of brain activity and excitability.
Topics & Concepts
RegulatorNeuroscienceFunction (biology)Central nervous systemCell biologyNervous systemImmune systemSecretionBiologyEndocrinologyImmunologyBiochemistryGeneNeuroscience and Neuropharmacology ResearchIon channel regulation and functionIon Channels and Receptors