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Design of a multi-epitope subunit vaccine for immune-protection against Leishmania parasite

Sunita Yadav, Jay Prakash, Harish Shukla, Kanhu Charan Das, Timir Tripathi, Vikash Kumar Dubey

2020Pathogens and Global Health51 citationsDOIOpen Access PDF

Abstract

cloning to check the expression of the final designed vaccine. The designed vaccine construct needs further experimental and clinical investigations to develop it as a safe and effective vaccine against VL infection.

Topics & Concepts

AdjuvantEpitopeLeishmania donovaniImmunogenicityVirologyImmune systemBiologyVisceral leishmaniasisIn silicoLeishmaniaVaccine efficacyVaccinationPeptide vaccineHIV vaccineImmunologyLeishmaniasisComputational biologyAntigenVaccine trialParasite hostingComputer scienceGeneGeneticsWorld Wide Webvaccines and immunoinformatics approachesResearch on Leishmaniasis StudiesMonoclonal and Polyclonal Antibodies Research
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