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Determination of empagliflozin in the presence of its organic impurities and identification of two degradation products using UHPLC-QTOF/MS

Joanna Wittckind Manoel, Gabriele Bordignon Primieri, Lívia Maronesi Bueno, Camila Ferrazza Alves Giordani, Júlia Medeiros Sorrentino, Alexsandro Dallegrave, Clésio Soldateli Paim, Elfrides Eva Scherman Schapoval, Cássia Virgínia Garcia, Martin Steppe

2020Microchemical Journal21 citationsDOI

Topics & Concepts

EMPAEmpagliflozinImpurityChromatographyChemistryDegradation (telecommunications)Detection limitAnalytical Chemistry (journal)Volume (thermodynamics)Electron microprobeOrganic chemistryMineralogyTelecommunicationsPhysicsComputer scienceDiabetes mellitusEndocrinologyQuantum mechanicsMedicineType 2 Diabetes MellitusAnalytical Methods in PharmaceuticalsDiabetes Treatment and ManagementAntibiotics Pharmacokinetics and Efficacy
Determination of empagliflozin in the presence of its organic impurities and identification of two degradation products using UHPLC-QTOF/MS | Litcius