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Cr(VI) induces ROS-mediated mitochondrial-dependent apoptosis in neuronal cells via the activation of Akt/ERK/AMPK signaling pathway

Shih-Chang Fu, Jui‐Ming Liu, Kuan-I Lee, Feng‐Cheng Tang, Kai‐Min Fang, Ching‐Yao Yang, Chin‐Chuan Su, Hsin‐Hung Chen, Ren‐Jun Hsu, Ya‐Wen Chen

2020Toxicology in Vitro77 citationsDOI

Topics & Concepts

Protein kinase BAMPKCell biologyReactive oxygen speciesChemistryApoptosisMAPK/ERK pathwayProtein kinase ACytochrome cAMP-activated protein kinaseProgrammed cell deathMitochondrionMitochondrial ROSPhosphorylationPI3K/AKT/mTOR pathwayBiologyMolecular biologyBiochemistryChromium effects and bioremediationHeavy Metal Exposure and ToxicityTrace Elements in Health
Cr(VI) induces ROS-mediated mitochondrial-dependent apoptosis in neuronal cells via the activation of Akt/ERK/AMPK signaling pathway | Litcius