Nanomodulators targeting endothelial WNT and pericytes to reversibly open the blood–tumor barrier for boosted brain tumor therapy
Rui Mu, Hang Sun, Yuteng Zeng, Yang Tong, Puxian Tang, Mei Zhao, Ziyan Lv, Ju Yu, Yanming Chen, Qing Lan, Xuechu Zhen, Liang Han
Topics & Concepts
Blood–brain barrierWnt signaling pathwayCancer researchDoxorubicinCancerEtoposideMedicineVascular permeabilityBrain tumorBreast cancerChemistryPathologyChemotherapyInternal medicineBiologySignal transductionCell biologyCentral nervous systemBarrier Structure and Function StudiesBrain Metastases and TreatmentNanoplatforms for cancer theranostics