Triptolide reduces PD-L1 through the EGFR and IFN-γ/IRF1 dual signaling pathways
Yongli Xie, Jiwei Ding, Jieke Gao, Jiantao Zhang, Shan Cen, Jinming Zhou
Topics & Concepts
TriptolidePD-L1Cancer researchSignal transductionIRF1STAT1PhosphorylationSTAT3ChemistryCell biologyImmunotherapyImmune systemBiologyImmunologyApoptosisBiochemistryTranscription factorGeneNatural Compounds in Disease TreatmentCytokine Signaling Pathways and InteractionsCancer Mechanisms and Therapy