Aryl Dance Reaction of Arylbenzoheteroles
Hikaru Nakahara, Junichiro Yamaguchi
Abstract
We report a 1,2-migration (aryl dance reaction) of the aryl group on heteroles. AlCl3 can efficiently convert C3-arylheteroles to C2-arylheteroles. Depending on the electron density of the substrate, conversion from C2- to C3-arylheteroles was also possible with catalytic Zn(OTf)2. A one-pot aryl dance/acylation or bromination and arylation/aryl dance cascade was also demonstrated.
Topics & Concepts
DanceArylChemistryAcylationSubstrate (aquarium)HalogenationCatalysisCascadeOrganic chemistryLiteratureGeologyArtAlkylChromatographyOceanographyCatalytic C–H Functionalization MethodsCatalytic Cross-Coupling ReactionsAsymmetric Synthesis and Catalysis