Natural Products from Endophytic Fungi Associated with Rubiaceae Species
Jacqueline Santos Cruz, Carla Amaral da Silva, Lidilhone Hamerski
Abstract
This review presents the chemical diversity and pharmacological properties of secondary metabolites produced by endophytic fungi associated with various genera of Rubiaceae. Several classes of natural products are described for these endophytes, although, this study highlights the importance of some metabolites, which are involved in antifungal, antibacterial, anti-protozoal activities; neurodegenerative diseases; cytotoxic activity; anti-inflammatory and antioxidant activity; and hyperglycemic control.
Topics & Concepts
RubiaceaePlant use of endophytic fungi in defenseBiologyAntifungalBotanyAntimicrobialTraditional medicineMicrobiologyMedicineMicrobial Natural Products and BiosynthesisAlkaloids: synthesis and pharmacologyNatural product bioactivities and synthesis